研究業績

2022年

学術論文

• "A new lanostane triterpenoid from the mushroom Hypholoma fasciculare"
  Wang, J, Wu, J., Tsutsumi, K., Choi, J-H, Hirai, H., Kobori, H.,Takikawa,Y., and Kawagishi, H.
  Biosci. Biotechnol. Biochem., in press (2022).
• "Potential of fairy chemicals as functional cosmetic ingredients: effect of 2-aza-8-oxohypoxanthine (AOH) on skin lightness"
  Aoshima, H., Ito, M., Ibuki, R., and Kawagishi, H.
  Int. J. Med. Mushr., in press (2022).
• "1,2,3-Triazine formation mechanism of a fairy chemical 2-azahypoxanthine in the fairy ring-forming fungus Lepista sordida"
  Ito, A., Choi, J-H., Yokoyama-Maruyama, W., Kotajima, M., Wu, J., Suzuki, T., Terashima, Y., Suzuki, H., Hirai, H., Nelson, D. C., Tsunematsu. Y., Watanabe, K., Asakawa, T., Ouchi, H., Inai, M., Dohra, H, and Kawagishi H.
  Org. Biomol. Chem., in press (2022).
• " RNA-Seq analysis of Phanerochaete sordida YK-624 degrades neonicotinoid pesticide acetamiprid, Environmental Technology"
  J. Wang, Y. Liu, R. Yin, N. Wang, T. Xiao, H. Hirai
  Environmental Technology, in press (2022). DOI:10.1080/09593330.2022.2026488
• "The fairy chemical imidazole-4-carboxamide inhibits the expression of Axl, PD-L1, and PD-L2 and improves response to cisplatin in cancer"
  Inoue, C., Yasuma, T., D'Alessandro-Gabazza, C. N., Toda, M., D'Alessandro, V. F., Inoue, R., Fujimoto, H., Kobori, H., Takeshita, A., Nishihama, K., Okano, Y., Wu, J., Kobayashi, T., Yano, Y., Kawagishi, H., and Gabazza, E. C.
  Cells 11, 347 (2022). DOI: 10.3390/cells11030374

2021年

学術論文

• "Transcriptomic analysis reveals ligninolytic enzymes of white-rot fungus Phanerochaete sordida YK-624 participating in bisphenol F biodegradation under ligninolytic conditions"
  Wang, J., Yin, R., Zhang, X., Wang, N., Xiao, P., Hirai, H., Xiao, T.
  Environ. Sci. Pollut. Res. Int. 28, 62390-62397 (2021). DOI:10.1007/s11356-021-15012-z
• "Ethanol fermentation by saprotrophic white-rot fungus Phanerochaete sordida YK-624 during wood decay as a system for short-term resistance to hypoxic conditions"
  Mori, T., Masuda, A., Kawagishi, H., Hirai, H.
  J. Biosci. Bioeng. 133, 64-69 (2021). DOI:10.1016/j.jbiosc.2021.10.002
• "Draft genome sequence of the white-rot fungus Phanerochaete sordida YK-624"
  Mori, T., Dohra, H., Suzuki, T., Kawagishi, H., Hirai, H.
  Microbiology Resource Announcements 42, e00842-21 (2021). DOI:10.1128/MRA.00842-21
• "Transcriptomics analysis reveals the high biodegradation efficiency of white-rot fungus Phanerochaete sordida YK-624 on native lignin"
  Wang, J., Suzuki, T., Yin, R., Dohra, H., Mori, T., Kawagishi, H., and Hirai, H.
  J. Biosci. Bioeng. 132, 253-257 (2021). DOI:10.1016/j.jbiosc.2021.05.009
• "Clinical evaluation of topical lotion containing 2-aza-8-oxohypoxanthine on skin barrier function against water loss"
  Aoshima, H., Ibuki, R. H., Ito, M., and Kawagishi, H.
  Cosmetics 8, 83 (2021). DOI:10.3390/cosmetics8030083
• "Improvement of saccharide yield from wood by simultaneous enzymatic delignification and saccharification using a ligninolytic enzyme and cellulase"
  Mori, T., Ikeda, K., Kawagishi, H., Hirai, H.
  J. Biosci. Bioeng. 132, 213-219 (2021). DOI:10.1016/j.jbiosc.2021.04.016
• "Safety evaluation of 2-aza-8-oxohypoxanthine by in vitro skin sensitization and human tests"
  Aoshima, H., Matsumoto, T., Ibuki, R. and Kawagishi, H.
  Fundam. Toxicol. Sci. 8, 123-133 (2021). DOI:10.2131/fts.8.123
• "The potential of 2-aza-8-oxohypoxanthine as a cosmetic ingredient"
  Aoshima, H., Ito, M., Ibuki, R. and Kawagishi, H.
  Cosmetics 8, 60 (2021). DOI:10.3390/cosmetics8030060
• "Quantification of ustalic acid, a chemotaxonomic marker, in Tricholoma ustale using liquid chromatography–mass spectrometry"
  Ito,T., Nagai, H., Aoki, W., Yamada, A., Kawagishi, H., Fukaya, M., and Konishi, H.
  J. Nat. Med. 75, 688-691 (2021). DOI:10.1007/s11418-021-01496-z.
• "S-Adenosylhomocysteine Analogue of a Fairy Chemical, Imidazole-4-carboxamide, as its Metabolite in Rice and Yeast and Synthetic Investigations of Related Compounds"
  Ouchi, H., Namiki, T., Iwamoto, K., Matsuzaki, N., Inai, M., Kotajima, M., Wu, J., Choi, J-H., Kimura, Y., Hirai,H., Xie, X., Kawagishi, H., and Kan,T
  J. Nat. Prod. 84, 453-458 (2021). DOI:10.1021/acs.jnatprod.0c01269
• "An efficient heterologous Escherichia coli-based expression system for lectin production from Pleurocybella porrigens"
  Suzuki, T., Nakamura, L., Inayoshi, S., Tezuka, Y., Choi, J-H., Dohra, H., Sasanami, T. Hirai, H., and Kawagishi H.
  Biosci. Biotechnol. Biochem. 85, 630-633 (2021). DOI:10.1093/bbb/zbaa058
• "White-rot fungus Phanerochaete chrysosporium metabolizes chloropyridinyl-type neonicotinoid insecticides by an N-dealkylation reaction catalyzed by two cytochrome P450s"
  T. Mori, H. Ohno, H. Ichinose, H. Kawagishi, H. Hirai
  Journal of Hazardous Materials 402, 123831 (2021). DOI:10.1016/j.jhazmat.2020.123831

2020年

学術論文

• "A fairy chemical suppresses retinal angiogenesis as a HIF inhibitor"
  Lee, D., Miwa, Y., Wu, J., Shoda, C., Jeong, H., Kawagishi, H., Tsubota, K., and Kurihara. T.
  Biomolecules 10, 1405 (2020). DOI:10.3390/biom10101405
• "木質バイオマスからのメタン発酵前処理に適した白色腐朽菌の選抜"
  森智夫，岩田実子，木村浩之，河岸和洋，平井浩文
  日本きのこ学会誌 28, 2, 56-61 (2020).
• "Biosynthesis of the fairy chemicals, 2-azahypoxanthine and imidazole-4-carboxamide, in the fairy ring-formingfungus Lepista sordida"
  Ito, A., Choi, J-H., Takemura,H., Kotajima,M., Wu, J., Tokuyama, S., Hirai, H., Asakawa, Ouchi, H., Inai, M., Kan, T., and Kawagishi, H.
  J. Nat. Prod. 83, 2469－2476 (2020). DOI:10.1021/acs.jnatprod.0c00394
• "Bitter compounds in two Tricholoma species, T. aestuans and T. virgatum"
  Oba, Y., Urai, M., Wu, J., Tomizawa, M., Kawagishi,H., and Hashimoto, K.
  J. Antibiotic. 73, 697-701 (2020).
• "Safety evaluation of 2-aza-8-oxohypoxanthine based on in vitro and human patch tests"
  Aoshima, H., Hyodo, S., Ibuki, R., Wu, J., Choi, J-H., Kawagishi, H.
  Fundam. Toxicol. Sci. 7, 5, 207-215 (2020). DOI:10.2131/fts.7.207
• "Axl and immune checkpoints inhibitors from the fruiting bodies of Pleurocybella porrigens"
  Ridwan, Y. A., Wu, J., Harada, E., D’Alessandro-Gabazza, C., Toda, M., Yasuma,T., Gabazza, E. C., Choi, J-H., Hirai, H., and Kawagishi, H.
  J. Antibiotic. 73, 733-736 (2020).
• "Effects of imidazole-4-carboxamide and 2-azahypoxanthine on the growth of Pinus densiflora seedlings and its ectomycorrhizal formation with Tricholoma matsutake"
  Nakano, S., Yamanaka, T., and Kawagishi, H.
  Mycoscience 61, 5, 259-263 (2020). DOI:10.1016/j.myc.2020.04.004
• "A Staphylococcus pro-apoptotic peptide induces acute exacerbation of pulmonary fibrosis"
  D’Alessandro-Gabazza, C., Kobayashi, T., Yasuma, T., Toda, M., Kim, H., Fujimoto, H., Hataji, O., Takeshita, A., Nishihama, K., Okano, Y., Okano, Y., Nishii, Y., Tomaru, A., Fujiwara, K., D'Alessandro, V. F., Abdel-Hamid, A., Ren, Y., Pereira, G., Wright, C., Hernandez, A., Fields, C., Yau, P., Wang, S., Mizoguchi, A., Fukumura, M., Ohtsuka, J., Nosaka, T., Kataoka, K., Kondoh, Y., Wu, J., Kawagishi, H., Yano, Y., Mackie, R., Cann, I., and Gabazza, E. C.
  Nature Commun 11, 1539 (2020).
• "Plant growth regulators and axl and immune checkpoint inhibitors from the edible mushroom Leucopaxillus giganteus"
  Malya, I. Y., Wu, J., Harada, E., Toda, M., D’Alessandro-Gabazza, C., Yasuma,T., Gabazza, E. C., Choi, J-H., Hirai, H., and Kawagishi, H.
  Biosci. Biotechnol. Biochem. 80, 7, 1332-1338 (2020). DOI:10.1080/09168451.2020.1743170
• "A biomimetic synthesis of chaxine and its related compounds"
  Niki, M., Hirata, Y., Nakazaki, A., Wu, J., Kawagishi, H., and Nishikawa, T.
  J. Org. Chem. 85, 7, 4848-4860 (2020). DOI:10.1021/acs.joc.9b03482
• "Self-fusion and fusion cell isolation of transformants derived from white rot fungus Phanerochaete sordida YK-624 by simple visual method"
  Mori, T., Kondo, O., Sumiya, T., Kawagishi, H., and Hirai, H.
  J. Bioscie. Bioeng. 129, 146-149 (2020). DOI:10.1016/j.jbiosc.2019.08.011
• "Inhibition of cholesteryl ester synthesis by polyacetylenes from Atractylodes rhizome"
  Nur, A.A.E., Ohshiro, T., Kobayashi, K., Wu, J., Wahyudin, E., Zhang, F., Hayashi, F., Kawagishi, H., and Tomoda, H.
  Bioorg. Med. Chem. Lett. 30, 126997 (2020). DOI:10.1016/j.bmcl.2020.126997
• "Medicinal mushroom, Grifola gargal (Agaricomycetes), lowers triglyceride in animal models of obesity and diabetes and in adults with prediabetes"
  Harada, E., Morizono, T., Kanno, Saito, M., and Kawagishi, H.
  Int. J. Med. Mushr. 22, 1, 79-91 (2020). DOI:10.1615/IntJMedMushrooms.2019033285